VA releases new findings on the connection between TBI and dementia

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VA and the Kristine Yaffe Lab at the University of California, San Francisco, have taken a new approach to understanding the association of mild traumatic brain injury (TBI) — with and without loss of consciousness (LOC) — with dementia among Veterans. Their recent study, one of the largest in the United States, included 178,779 Veterans in the VA health care system who were diagnosed with various levels of TBI severity.
The study found that TBI with and without LOC are both associated with a heightened risk of developing dementia. Even mild TBI without LOC was associated with more than a twofold increase in the risk of a dementia diagnosis.

The study was part of the Chronic Effects of Neurotrauma Consortium (CENC), a federally funded research project devised to address the long-term effects of mild TBI in military service members and Veterans. CENC is jointly funded by VA and the Department of Defense.

TBI overview
TBI is a complex physiological condition that can arise when a brain experiences trauma, either directly or indirectly, during any of a variety of moderate to catastrophic events. TBI has been researched and studied in-depth by some of the world’s leading neurologists, neuropsychologists, neuropsychiatrists and other leading mental health experts. Their goal is to develop treatments, tools and resources to help those affected by TBI return to their previous, or close to their previous, quality of life and cognitive ability. TBI among Veterans is a key focus area of VA physical and mental health care, and VA conducts research every day to help unravel the intricacies of TBI’s symptoms and effects.
In the past 10 years, researchers and clinicians have confirmed that TBI may be a risk factor for dementia, but they have yet to determine why. Some professionals think dementia may be related to the injury itself, while others believe that head trauma may cause toxic and abnormal proteins associated with dementia to build


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